Info: 90 Capsules - 384 mg
New! A metabolite compound, Urolithin A has been the subject of a rapidly increasing number of studies indicating it improves muscle strength and has a beneficial impact on certain biomarkers of cellular health, particularly in middle-aged and older people, and is thus heralded as an anti-aging nutritional support formula.
Info: 90 Capsules - 384 mg
New! A metabolite compound, Urolithin A has been the subject of a rapidly increasing number of studies indicating it improves muscle strength and has a beneficial impact on certain biomarkers of cellular health, particularly in middle-aged and older people, and is thus heralded as an anti-aging nutritional support formula.
Product Notes:
Urolithin A with NMN, Resveratol & Spermidine
Sold in some markets under the trade name "Mitopure," Urolithin A is a natural postbiotic compound (produced by beneficial bacteria during the course of fermentation) that promotes mitochondrial function (the parts of our cells which produce usable energy from food, among other things) and mitophagy (the selective recycling of those mitochondria).
AOR (Advanced Orthomolecular Research) is the first company to issue a licensed version for the Canadian market. It is called Urolithin A Plus because it's also accompanied by several other well-studied bioactive compounds for cellular health, for a synergistic effect. These include:
- Resveratrol, the strong antioxidant found in grapes and certain berries and herbs that can help protect our cells from free radicals produced by UV rays, pollution, and certain medications and foods; it's presented here in its active "trans-" form;
- NMN (Nicotinamide Mononucleotide) and Wheat Germ, providing Spermidine: a triad to assist cellular and genetic metabolism, which is explained in more detail in AOR's video and our accompanying transcript.
Mitopure™ is a trademark of Amazentis SA in the USA.
AOR Urolithin A+ Ingredients:
Each 3 Capsule DAILY Dose provides:
Urolithin A: 1000 mg
Resveratrol: 50 mg
Wheat Germ: 100 mg, providing:
- 1.2 mg Spermidine
Nicotinamide Mononucleotide: 100 mg
Non-medicinal ingredients: Microcrystalline cellulose, sodium stearyl fumarate, silicon dioxide. Capsule: Hypromellose.
Vegan. GMO-free. Gluten-free.
The fermentation to produce this Urolithin A (UA) is achieved by using gut-derived bacteria to consume foods which contain ellagitannin, such as pomegranate, strawberry, raspberry, blackberry, muscadine grapes, or walnuts. In chemistry terms, the resulting compound is known as 2-Biphenylcarboxylic acid, 2',4,4'-trihydroxy-, delta-lactone).
Suggested Usage:
Adults: Take one capsule three times a day, either with or without food, or as directed by a healthcare practitioner. Do not crush, blend or mix the capsules - swallow them whole. Do not exceed daily dose, unless instructed to by a healthcare practitioner.
Warnings:
Consult a healthcare practitioner prior to use if you are pregnant or breastfeeding or trying to conceive; or if you have a Vitamin B12 deficiency; or if you have malignant neoplasms, serious infections, malignant tumors, cardiac failure, myocardial infarction, diabetes, a history of seizures or epilepsy, or other chronic medical conditions; or if you are taking prescription medications (since resveratrol may alter their effectiveness).
Health Canada Natural Product Number: 80128555.
Supporting Science:
D'Amico, Davide et al. “Impact of the Natural Compound Urolithin A on Health, Disease, and Aging.” Trends in Molecular Medicine, 2021.
Kothe, Breanne et al. “Urolithin A as a Potential Agent for Prevention of Age-Related Disease: A Scoping Review.” Cureus, 2023.
Singh, Anurag et al. “Urolithin A improves muscle strength, exercise performance, and biomarkers of mitochondrial health in a randomized trial in middle-aged adults.” Cell Reports. Medicine, 2022.
Zhao, Haotian et al. “Pharmacological Effects of Urolithin A and Its Role in Muscle Health and Performance: Current Knowledge and Prospects.” Nutrients, 2023.