Info: 60 Vegetarian Capsules - 150 mg NMN
New! NAD+ is a critical coenzyme present in every cell of our bodies that's involved in hundreds of metabolic processes and enables them to produce energy. But we produce a lot less of it as we age, which can lead to a cascade of effects associated with aging. RegenerLife NMN SURGE features a cutting-edge form of vitamin B3 which gets easily converted to NAD+, to help slow down or even reverse some of those changes.
Info: 60 Vegetarian Capsules - 150 mg NMN
New! NAD+ is a critical coenzyme present in every cell of our bodies that's involved in hundreds of metabolic processes and enables them to produce energy. But we produce a lot less of it as we age, which can lead to a cascade of effects associated with aging. RegenerLife NMN SURGE features a cutting-edge form of vitamin B3 which gets easily converted to NAD+, to help slow down or even reverse some of those changes.
Product Notes:
Natural Factors NMN Surge: Metabolically Active Nicotinamide Mononucleotide & NAD Precursor
NMN is a nucleotide derived from ribose and nicotinamide. Like nicotinamide riboside (Niagen), NMN is a derivative of niacin, and a precursor to NAD+.
As we age, the ability of our blood vessels to deliver nutrients to muscles decreases, resulting in a loss of endurance. According to recent research, the naturally-occurring compound NMN (nicotinamide mononucleotide) boosts metabolism, blood vessel growth, cardiovascular functions, and cell maintenance in mice. Research continues into NMN's anti-aging properties and its potential use for human health.
The leading causes of unhealthy aging are thought to be DNA and telomere damage, and mitochondrial dysfunction. By the same token, some natural compounds in our bodies are pivotal to optimal health and healthy biological aging – most notably NAD+ (nicotinamide adenine dinucleotide), whose levels plummet in half by the time we reach middle age.
That can not only leave us more fatigued, but also reduce our metabolism, which can lead to weight gain, muscle loss, cognitive decline, and an increased risk of developing diabetes.
Fortunately, numerous studies have demonstrated that boosting NAD+ levels can reverse mitochondrial dysfunction and improve insulin sensitivity. One of the most effective ways of doing that is by supplementing with one of its precursors, NMN (nicotinamide mononucleotide), which can get absorbed quite rapidly to be converted to NAD+. It's also been demonstrated that NMN supplements are more effective for this purpose than nicotinamide riboside (or NR: another NAD+ precursor).
NMN in Canada - Is it Legal?
NMN is relatively new to Canada but is now licensed for sale as a dietary supplement. Natural Factors RegenerLife NMN Surge has been issued the Natural Product Number (NPN) 80121612 by Health Canada.
Having been available for some time in the USA, NMN is not strictly banned, but the status of NMN supplements is currently being reviewed and debated there. The US FDA is weighing usage of NMN as a supplement against claims from pharmaceutical producers that the compound was first registered as a prescription drug in that country. This regulatory debate (and initial rulings that it is not considered a dietary supplement) has led some US retailers to stop offering NMN supplements.
Related: See Tru Niagen, NOW NADH, Natural Factors RegenerLife, AOR NMN+ Wheat Germ, and GlyNAC (Glycine & NAC).
The technical name for β-NMN (beta-nicotinamide mononucleotide) in licensed natural health products is 3-(Aminocarbonyl)-1-(5-O-phosphonato-beta-D-ribofuranosyl)pyridinium.
Ingredients:
Medicinal ingredients: NMN ... 150 mg.
Nicotinamide Mononucleotide: The chemical formula for NMN is: 3-(Aminocarbonyl)-1-(5-O-phosphonato-beta-D-ribofuranosyl)pyridinium)
Non-medicinal ingredients: Vegetarian capsule (carbohydrate gum [cellulose], purified water), microcrystalline cellulose, vegetable grade magnesium stearate (lubricant), stearic acid, silica.
Natural Factors RegenerLIFE NMNSurge contains no artificial colours, preservatives, or sweeteners; no dairy, starch, sugar, wheat, gluten, yeast, soy, corn, egg, fish, shellfish, animal products, salt, tree nuts, or GMOs. Suitable for vegetarians/vegans.
Suggested Usage:
Adults: Take 1 capsule twice daily, or as directed by a healthcare practitioner.
Warnings:
Keep NMN Surge out of reach of children Consult a healthcare practitioner prior to using NMN supplements if you are pregnant or breastfeeding, or have diabetes.
Supporting Science:
Fukamizu, Yuichiro et al. “Safety evaluation of β-nicotinamide mononucleotide oral administration in healthy adult men and women.” Scientific Reports, 2022.
Soma, Mounica, and Satya Kumar Lalam. “The role of nicotinamide mononucleotide (NMN) in anti-aging, longevity, and its potential for treating chronic conditions.” Molecular Biology Reports, 2022.
Yi, Lin et al. “The efficacy and safety of β-nicotinamide mononucleotide (NMN) supplementation in healthy middle-aged adults: a randomized, multicenter, double-blind, placebo-controlled, parallel-group, dose-dependent clinical trial.” GeroScience, 2023.
Yoshino, Mihoko et al. “Nicotinamide mononucleotide increases muscle insulin sensitivity in prediabetic women.” Science, 2021.