Info: 30 Vegi-Caps (1 mg Each)
Folate and vitamin B12 are a classic duo, working synergistically in the body to aid in DNA synthesis, metabolism, normal red blood cell production, and cognitive functions. Folate supports cardiovascular health, as well as reduces the risk of neural tube defects in women both prior to becoming pregnant and during pregnancy. New research indicates it may even help reduce knee pain and stiffness in older adults with osteoarthritis!*
Info: 30 Vegi-Caps (1 mg Each)
Folate and vitamin B12 are a classic duo, working synergistically in the body to aid in DNA synthesis, metabolism, normal red blood cell production, and cognitive functions. Folate supports cardiovascular health, as well as reduces the risk of neural tube defects in women both prior to becoming pregnant and during pregnancy. New research indicates it may even help reduce knee pain and stiffness in older adults with osteoarthritis!*
Product Notes:
Bioactive Folate & Vitamin B12
BioFolate contains the ideal ratio of folate to vitamin B12 for optimal function in the body; this ensures that a surplus of folate is not masking a vitamin B12 deficiency as this may lead to nerve damage.
Note, Bio-Folate from AOR contains 5-MTHF (also known as methyl folate), which is the form of this vitamin (B9) that's naturally produced in the body, making it highly absorbable and far more efficiently utilized in the body than folic acid (which requires a multi-step conversion process to function properly, using an enzyme not everyone produces enough of).
Ingredients:
Each BioFolate capsule contains:
5-Methyltetrahydrofolate (5-MTHF): 1 mg
Vitamin B12 (methylcobalamin): 2.4 mcg
Non-medicinal ingredients: microcrystalline cellulose, silicon dioxide. / Capsule: hypromellose. Contains no wheat, gluten, corn, nuts, peanuts, sesame seeds, sulphites, mustard, soy, eggs, fish, shellfish or any animal byproduct.
Suggested Usage:
Adults: Take one capsule per day with food, or as directed by a qualified healthcare practitioner.
Warnings:
Folate supplementation can mask a vitamin B12 deficiency. Consult a health care practitioner prior to using AOR BioFolate supplement if you are uncertain whether or not you are taking adequate vitamin B12 or if you are pregnant or breastfeeding.
Health Canada Natural Product Number: 80030511.
*Supporting Science:
A new analysis of the data from an earlier two-year Vitamin D study of 400 Australians between the ages of 50 and 79 who have osteoarthritis found,
"Folate intake was correlated with reductions in overall knee pain, dysfunction, and stiffness, as well as decreased levels of Leptin and Apelin. Additionally, it was associated with enhanced leg muscle strength and diminished feet and low back pain. ...Within the subsets of overall knee pain, a significant relationship was identified between folate intake and the reduction of pain experienced when ascending or descending stairs and standing for two years."
Even though the subjects were principally getting their folate from foods, the study's authors indidcate they believe their data provides good grounds for advocating for those with knee OA to supplement with folate daily to potentially ameliorate their condition, noting, "Individuals suffering from symptomatic knee OA could experience significant relief in daily symptoms, such as knee pain and depression, which considerably impair their quality of life, following folate supplementation."
See: Liu, Z., et al. "Associations between folate intake and knee pain, inflammation mediators and comorbid conditions in patients with symptomatic knee osteoarthritis." BMC Musculoskeletal Disorders, 2024.